Technical Bulletin: The HPME® Advantage
Human mesenchymal stem cells (hMSCs) are a promising tool for therapeutic applications in cell-based therapy and regenerative medicine.
A Novel Approach for Expansion of High Quality Mesenchymal Stem Cells
One size does not fit all: developing a cell-specific niche for in vitro study of cell behavior.
Matrix Biology 2016
Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts.
Journal of Bone Mineral Research 2007
Reconstitution of marrow-derived extracellular matrix ex-vivo: A robust culture system for expanding large scale highly functional human mesenchymal stem cells.
Stem Cells and Development 2010
Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditions.
Stem Cell Research and Therapy 2015
Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix.
Federation of American Societies for Experimental Biology 2011